Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220449 | 0.82 | POLB (0.35) | KDM4EPOLBATMADORA3ADORA2A | |
| SCHEMBL10916999 | 0.74 | ALDH1A1 (0.56) | HSD17B10KDM4EALDH1A1POLBTSHR | |
| SCHEMBL14950486 | 0.72 | POLB (0.56) | HSD17B10KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL10310217 | 0.72 | POLB (0.56) | HSD17B10KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL10914209 | 0.72 | POLB (0.38) | KDM4EALDH1A1POLBATMTSHR | |
| SCHEMBL10920007 | 0.71 | ATM (0.39) | HSD17B10KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL10917251 | 0.71 | CYP1A1 (0.45) | HSD17B10KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL10916878 | 0.71 | KDM4E (0.40) | HSD17B10KDM4EALDH1A1POLBATM | |
| SCHEMBL10919523 | 0.70 | POLB (0.37) | ALDH1A1HPGDPOLBATMCA1 | |
| SCHEMBL10914651 | 0.70 | CYP1A1 (0.39) | HSD17B10KDM4EALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576766-B1 | Competitive binding of phosphotyrosine-containing protein; veterinary medicine | ARIAD PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |