Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6287392 | 0.75 | F11 (0.52) | ADORA2AADORA1ADORA2BPTGDR2GRM5 | |
| SCHEMBL6283502 | 0.73 | ADORA2A (0.45) | ADORA2AADORA1ADORA2BPTGDR2GRM5 | |
| SCHEMBL8205342 | 0.73 | CDK4 (0.54) | ADORA2AADORA1ADORA2BCLK4CTSS | |
| SCHEMBL7430278 | 0.70 | IDO1 (0.43) | CLK4F11PIN1 | |
| SCHEMBL5510284 | 0.69 | PTGS2 (0.51) | PTGDR2 | |
| SCHEMBL4854539 | 0.68 | PPARG (0.47) | ADORA2AADORA1ADORA2BCLK4CTSS | |
| SCHEMBL12636667 | 0.67 | PRF1 (0.50) | ADORA2AADORA1ADORA2BCLK4CTSS | |
| SCHEMBL6237896 | 0.67 | ADORA2A (0.51) | ADORA2AADORA1ADORA2BCLK4CFTR | |
| SCHEMBL24763023 | 0.67 | ADORA1 (0.58) | ADORA2AADORA1ADORA2BCLK4CFTR | |
| SCHEMBL19169352 | 0.67 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BCLK4CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534535-B1 | Administering indole derivative as anticoagulant | MILLENNIUM PHARMACEUTICALS, INC. | 2003-03-18 | — | — | US | disclosed |
| WO-2001012600-A9 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC (US) | 2002-09-12 | — | — | WO | disclosed |
| WO-2001012600-A1 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2001-02-22 | — | — | WO | disclosed |