Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395177 | 0.79 | IDO1 (0.46) | IDO1MAP4K4GSK3ACLK4MAOB | |
| SCHEMBL30239372 | 0.75 | CHEK1 (0.57) | IDO1MAP4K4GSK3ACLK4MAOB | |
| SCHEMBL24963400 | 0.75 | CHEK1 (0.57) | IDO1MAP4K4GSK3ACLK4MAOB | |
| SCHEMBL7404293 | 0.75 | F11 (0.52) | IDO1MAP4K4GSK3ACLK4FASN | |
| SCHEMBL7220451 | 0.70 | ADORA2A (0.43) | CLK4F11PIN1 | |
| SCHEMBL16905206 | 0.69 | CLK4 (0.52) | IDO1MAP4K4CLK4MAOBPGR | |
| SCHEMBL8807143 | 0.68 | IDO1 (0.53) | IDO1MAP4K4GSK3ACLK4MAOB | |
| SCHEMBL5269506 | 0.68 | L3MBTL1 (0.59) | IDO1MAP4K4GSK3ACLK4MAOB | |
| SCHEMBL8205342 | 0.67 | CDK4 (0.54) | IDO1CLK4MAOBF11PIN1 | |
| SCHEMBL27518736 | 0.67 | LRRK2 (0.49) | IDO1CLK4MAOBPGRF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001012600-A9 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC (US) | 2002-09-12 | — | — | WO | disclosed |
| WO-2001012600-A1 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2001-02-22 | — | — | WO | disclosed |