Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 14/20 | 0.69 |
| ▸ | THRA | P10827 | 13/20 | 0.63 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TPMT | P51580 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073649 | 0.90 | THRB (0.61) | THRBTHRAPPARGHSD17B10ALOX15 | |
| SCHEMBL1302320 | 0.85 | THRB (0.56) | THRBTHRAPPARGHSD17B10ALOX15 | |
| SCHEMBL28680697 | 0.83 | HSP90AB1 (0.56) | THRBTHRAHSD17B10ALOX15TSHR | |
| SCHEMBL7220264 | 0.83 | THRB (0.53) | THRBTHRAPPARGHSD17B10ALOX15 | |
| SCHEMBL5859452 | 0.82 | THRB (0.62) | THRBTHRAPPARGPTGS1AKR1C3 | |
| SCHEMBL287411 | 0.80 | THRB (0.49) | THRBTHRAPPARGTSHRPTGS1 | |
| SCHEMBL1525495 | 0.79 | GAA (0.57) | THRBTHRAPPARGHSD17B10ALOX15 | |
| SCHEMBL8081551 | 0.78 | GAA (0.61) | THRBTHRAPPARGHSD17B10TSHR | |
| SCHEMBL499116 | 0.78 | GAA (0.61) | HSD17B10ALOX15TSHR | |
| SCHEMBL4896480 | 0.78 | THRB (0.64) | THRBTHRAPPARGHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943228-B | Alkaloid pulmonin B derivative, synthesis thereof and application thereof in preventing and treating plant virus and germ diseases | 天津师范大学 | 2023-10-27 | — | — | CN | claimed |
| CN-113943229-B | Synthesis of alkaloid pulmonarin B and application of alkaloid pulmonarin B in prevention and treatment of plant virus and germ diseases | 天津师范大学 | 2025-02-07 | — | — | CN | disclosed |
| CN-113943229-A | Synthesis of alkaloid pulmonarinn B and application of alkaloid pulmonarinn B in prevention and treatment of plant viruses and bacterial diseases | 天津师范大学 | 2022-01-18 | — | — | CN | disclosed |
| US-6596734-B1 | Method for stimulating, regulating and modulating metabolism of fats in adipose tissue in mammals, comprising administering to a mammal an effective amount of a beta 3- adrenoreceptor agonist | MOLECULAR DESIGN INTERNATIONAL, INC. | 2003-07-22 | — | — | US | disclosed |