Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.53 |
| ▸ | THRA | P10827 | 8/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220499 | 0.83 | THRB (0.69) | THRBTHRAHSD17B10TSHRALOX15 | |
| SCHEMBL28680697 | 0.81 | HSP90AB1 (0.56) | THRBTHRAHSD17B10TSHRALOX15 | |
| SCHEMBL192064 | 0.79 | PTGS2 (0.53) | MAPT | |
| SCHEMBL5899089 | 0.78 | THRB (0.49) | THRBTHRAHSD17B10ALOX15MAPT | |
| SCHEMBL1462899 | 0.77 | HDAC1 (0.57) | MAPTHPGD | |
| SCHEMBL22594983 | 0.75 | LMNA (0.37) | THRBTHRAMAPTHPGDHTT | |
| SCHEMBL26623841 | 0.75 | HSP90AB1 (0.49) | THRBTHRAHSD17B10TSHRALOX15 | |
| SCHEMBL28706052 | 0.75 | LMNA (0.49) | THRBTHRAHSD17B10TSHRALOX15 | |
| SCHEMBL1461660 | 0.75 | ALDH1A1 (0.46) | — | |
| SCHEMBL985767 | 0.75 | TPMT (0.55) | HSD17B10TSHRMAPTHPGDTPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596734-B1 | Method for stimulating, regulating and modulating metabolism of fats in adipose tissue in mammals, comprising administering to a mammal an effective amount of a beta 3- adrenoreceptor agonist | MOLECULAR DESIGN INTERNATIONAL, INC. | 2003-07-22 | — | — | US | disclosed |