Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 4/20 | 0.40 |
| ▸ | MMP9 | P14780 | 4/20 | 0.40 |
| ▸ | MMP8 | P22894 | 4/20 | 0.40 |
| ▸ | MMP13 | P45452 | 4/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL542639 | 0.71 | SMN1; SMN2 (0.73) | NPSR1SMN1; SMN2MMP2MMP9MMP8 | |
| SCHEMBL15569546 | 0.69 | NPSR1 (0.56) | NPSR1GLASMN1; SMN2TLR9MMP2 | |
| SCHEMBL5443745 | 0.66 | MMP2 (0.70) | NPSR1SMN1; SMN2MMP2MMP9MMP8 | |
| SCHEMBL13651912 | 0.66 | GLA (0.42) | NPSR1GLASMN1; SMN2TLR9LMNA | |
| SCHEMBL7220662 | 0.65 | NPSR1 (0.41) | NPSR1GLASMN1; SMN2TLR9MMP2 | |
| SCHEMBL29002709 | 0.65 | GLA (0.44) | NPSR1GLASMN1; SMN2GRM2ALDH1A1 | |
| SCHEMBL8515475 | 0.64 | GLA (0.40) | NPSR1GLASMN1; SMN2MMP2MMP9 | |
| SCHEMBL10590941 | 0.64 | LDHA (0.46) | NPSR1GLASMN1; SMN2TLR9ALDH1A1 | |
| SCHEMBL19559791 | 0.64 | MMP2 (0.45) | NPSR1GLASMN1; SMN2MMP2MMP9 | |
| SCHEMBL1603072 | 0.63 | HSD11B1 (0.49) | NPSR1GLASMN1; SMN2CRBNGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6504046-B1 | Cyclization of nitriles using acids, to form oxazolinone chemical intermediates such as 2-phenyl-4-isopropyl-4-methyl-1,3-oxazol-5-one, used as fungicides | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-07 | — | — | US | disclosed |
| EP-1092705-A1 | PROCESS FOR THE PREPARATION OF AMIDES | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |