Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.45 |
| ▸ | YAP1 | P46937 | 3/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.38 |
| ▸ | CETP | P11597 | 3/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186688 | 0.85 | GPR119 (0.46) | GPR119YAP1P2RX7PRMT5CETP | |
| SCHEMBL6190064 | 0.79 | GPR119 (0.48) | GPR119YAP1PRMT5STS | |
| SCHEMBL6187450 | 0.77 | GPR119 (0.47) | GPR119YAP1PRMT5STS | |
| SCHEMBL6187724 | 0.73 | GPR119 (0.46) | GPR119PRMT5CETPALK | |
| SCHEMBL5868120 | 0.71 | KMT2A (0.52) | GPR119YAP1STS | |
| SCHEMBL7220777 | 0.71 | GPR119 (0.50) | GPR119YAP1P2RX7PRMT5CETP | |
| SCHEMBL8121326 | 0.71 | GPR119 (0.51) | GPR119YAP1CETPALKSTS | |
| SCHEMBL6186695 | 0.71 | GPR119 (0.49) | GPR119YAP1P2RX7PRMT5CETP | |
| SCHEMBL6186844 | 0.71 | F10 (0.56) | GPR119YAP1P2RX7 | |
| SCHEMBL6186841 | 0.71 | F10 (0.56) | GPR119YAP1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562828-B1 | Novel amidine compound having a blood coagulation factor Xa inhibitory activity | JAPAN TOBACCO INC. (JP) | 2003-05-13 | — | — | US | disclosed |