Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 3/20 | 0.39 |
| ▸ | CETP | P11597 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220777 | 0.89 | GPR119 (0.50) | GPR119ALKP2RX7YAP1CETP | |
| SCHEMBL6186688 | 0.82 | GPR119 (0.46) | GPR119ALKP2RX7YAP1CETP | |
| SCHEMBL8120896 | 0.76 | GPR119 (0.52) | GPR119ALKP2RX7YAP1CETP | |
| SCHEMBL6188104 | 0.75 | GPR119 (0.57) | GPR119ALKCETP | |
| SCHEMBL6192978 | 0.72 | GPR119 (0.51) | GPR119YAP1HTTSTS | |
| SCHEMBL8114017 | 0.71 | GPR119 (0.59) | GPR119ALKCETP | |
| SCHEMBL6954502 | 0.71 | GPR119 (0.61) | GPR119ALKCETP | |
| SCHEMBL30011218 | 0.71 | GPR119 (0.54) | GPR119ALKP2RX7YAP1CETP | |
| SCHEMBL7220781 | 0.71 | GPR119 (0.45) | GPR119ALKP2RX7YAP1CETP | |
| SCHEMBL8113514 | 0.71 | GPR119 (0.58) | GPR119ALKCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070714-A9 | AMIDINE COMPOUNDS | JAPAN TOBACCO INC. (JP) | 2005-10-19 | — | — | EP | disclosed |
| US-20040006099-A1 | Amidine compounds | JAPAN TOBACCO INC. | 2004-01-08 | — | — | US | disclosed |
| US-6562828-B1 | Novel amidine compound having a blood coagulation factor Xa inhibitory activity | JAPAN TOBACCO INC. (JP) | 2003-05-13 | — | — | US | disclosed |
| EP-1070714-A1 | AMIDINE COMPOUNDS | JAPAN TOBACCO INC. (JP) | 2001-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006099-A1 | Amidine compounds | F2, SERPINC1, F12 | GPR119 2900/4885ALK 2526/4885P2RX7 2855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.