Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7213661 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2GAALMNADPP4KMT2A | |
| SCHEMBL13218344 | 0.75 | PIK3CD (0.48) | POLBHTTSMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL103478 | 0.74 | POLB (0.47) | POLBHTTSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL8097337 | 0.72 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNADPP4KMT2A | |
| SCHEMBL23890495 | 0.71 | LMNA (0.56) | POLBHTTSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL7220027 | 0.70 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNADPP4KMT2A | |
| SCHEMBL10270127 | 0.70 | ROCK2 (0.47) | POLBHTTSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL22875389 | 0.70 | ROCK2 (0.47) | POLBHTTSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL1233979 | 0.70 | POLB (0.44) | POLBHTTSMN1; SMN2GAALMNA | |
| SCHEMBL20781407 | 0.69 | HSD17B10 (0.38) | POLBHTTSMN1; SMN2GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6504046-B1 | Cyclization of nitriles using acids, to form oxazolinone chemical intermediates such as 2-phenyl-4-isopropyl-4-methyl-1,3-oxazol-5-one, used as fungicides | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-07 | — | — | US | disclosed |
| EP-1092705-A1 | PROCESS FOR THE PREPARATION OF AMIDES | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |