Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1871362 | 0.93 | RAB9A (0.46) | RAB9AALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL687133 | 0.85 | KDM4E (0.48) | RAB9AALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL27959055 | 0.79 | MAPT (0.50) | RAB9AALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL5374097 | 0.79 | QPCT (0.48) | RAB9AALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL352343 | 0.77 | ALDH1A1 (0.44) | RAB9AALDH1A1SMN1; SMN2KDM4EHTT | |
| Dimedazol SCHEMBL312977 | 0.77 | MAPT (0.56) | RAB9AALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL7020295 | 0.77 | KDM4E (0.41) | RAB9AALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL13948934 | 0.76 | KDM4E (0.61) | RAB9AALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL4916674 | 0.76 | MAPT (0.50) | RAB9AALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL30798836 | 0.76 | MAPT (0.54) | RAB9AALDH1A1SMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250025443-A1 | COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES | Clear Creek Bio, Inc. (US) | 2025-01-23 | — | — | US | disclosed |
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |
| CN-114630823-A | GLP-1R modulating compounds | 吉利德科学公司 | 2022-06-14 | — | — | CN | disclosed |
| US-20210246122-A1 | Triazine Compounds and Uses Thereof | Aduro Biotech, Inc. (US) | 2021-08-12 | — | — | US | disclosed |
| EP-3810600-A1 | TRIAZINE COMPOUNDS AND USES THEREOF | Aduro BioTech, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |
| US-6610692-B1 | Anticoagulants | MERCK & CO., INC. | 2003-08-26 | — | — | US | disclosed |
| EP-1124822-A4 | THROMBIN INHIBITORS | MERCK & CO INC (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1124822-A1 | THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026211-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2000-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246122-A1 | Triazine Compounds and Uses Thereof | IL5, IL15, TLR5 | RAB9A 4301/4885ALDH1A1 2419/4885SMN1; SMN2 965/4885 |
| US-20250025443-A1 | COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES | ACE, PREP, PEPD | RAB9A 3136/4885ALDH1A1 2460/4885SMN1; SMN2 4601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.