Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16414450 | 0.88 | NOS3 (0.42) | NOS3NOS1NOS2CYP3A4CYP2D6 | |
| SCHEMBL19007329 | 0.85 | NOS3 (0.43) | NOS3NOS1NOS2CYP3A4CYP2D6 | |
| SCHEMBL16477747 | 0.83 | PTGS1 (0.39) | NOS3NOS1NOS2CYP3A4CYP2D6 | |
| SCHEMBL18068020 | 0.83 | NOS3 (0.38) | NOS3NOS1NOS2CYP3A4CYP2D6 | |
| SCHEMBL25884519 | 0.81 | NOS3 (0.40) | NOS3NOS1NOS2CYP3A4CYP2D6 | |
| SCHEMBL18068052 | 0.79 | ESR1 (0.36) | NOS3NOS1NOS2CYP3A4CYP2D6 | |
| SCHEMBL21646563 | 0.79 | SMN1; SMN2 (0.35) | NOS3NOS1NOS2CYP3A4CYP2D6 | |
| SCHEMBL30147946 | 0.79 | SMN1; SMN2 (0.35) | NOS3NOS1NOS2CYP3A4CYP2D6 | |
| SCHEMBL4045335 | 0.78 | NOS3 (0.34) | NOS3NOS1NOS2CYP3A4CYP2D6 | |
| SCHEMBL4049194 | 0.78 | NOS3 (0.34) | NOS3NOS1NOS2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026090602-A1 | PIGMENTED RESIN AND CATALYST COMPOSITIONS | MATERIA, INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| EP-3110862-B1 | ADHESION PROMOTER COMPOSITIONS FOR CYCLIC OLEFIN RESIN COMPOSITIONS | ExxonMobil Product Solutions Company (US) | 2026-04-01 | — | — | EP | disclosed |
| EP-4683900-A2 | ROMP AND THERMAL INSULATION COMPOSITIONS AND MATERIALS AND USE THEREOF | Materia, Inc. (US) | 2026-01-28 | — | — | EP | disclosed |
| WO-2025245037-A1 | CYCLIC OLEFIN COMPOSITIONS, ROMP COMPOSITIONS THEREOF, AND APPLICATIONS THEREOF | MATERIA, INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| EP-4194092-B1 | SYNTHESIS AND CHARACTERIZATION OF METATHESIS CATALYSTS | UMICORE AG & CO KG (DE) | 2025-10-22 | — | — | EP | disclosed |
| EP-2970522-B1 | IN-MOLD COATING OF ROMP POLYMERS | MATERIA INC (US) | 2025-05-21 | — | — | EP | disclosed |
| US-20250122402-A1 | LONG SHELF-LIFE STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS CONTAINING PYRIDINE LIGATED PALLADIUM COMPOUNDS | PROMERUS, LLC (US) | 2025-04-17 | — | — | US | disclosed |
| EP-3013886-B1 | THERMAL INSULATION | MATERIA INC (US) | 2025-03-26 | — | — | EP | disclosed |
| EP-2961778-B1 | METAL CARBENE OLEFIN METATHESIS TWO CATALYST COMPOSITION | MATERIA INC (US) | 2025-02-26 | — | — | EP | disclosed |
| US-20250026871-A1 | CYCLIC RUTHENIUM BENZYLIDENE INITIATORS FOR ENHANCED RING EXPANSION METATHESIS POLYMERIZATION | UNIVERSITY OF WASHINGTON (US) | 2025-01-23 | — | — | US | disclosed |
| US-6946533-B2 | Synthesis of macrocyclic polymers by ring insertion polymerization of cyclic olefin monomers | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2005-09-20 | — | — | US | disclosed |
| EP-1543043-A2 | SYNTHESIS OF MACROCYCLIC POLYMERS BY RING INSERTION POLYMERIZATION OF CYCLIC OLEFIN MONOMERS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2005-06-22 | — | — | EP | disclosed |
| EP-1497299-A2 | CROSS-METATHESIS OF OLEFINS DIRECTLY SUBSTITUTED WITH AN ELECTRON-WITHDRAWING GROUP USING TRANSITION METAL CARBENE CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2005-01-19 | — | — | EP | disclosed |
| EP-0891970-B1 | Process for producing alkenylsubstituted pyridine derivatives | SUMITOMO CHEMICAL CO (JP) | 2004-10-13 | — | — | EP | disclosed |
| US-20040132934-A1 | Synthesis of macrocyclic polymers by ring insertion polymerization of cyclic olefin monomers | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2004-07-08 | — | — | US | disclosed |
| WO-2004013198-A2 | SYNTHESIS OF MACROCYCLIC POLYMERS BY RING INSERTION POLYMERIZATION OF CYCLIC OLEFIN MONOMERS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2004-02-12 | — | — | WO | disclosed |
| US-20030236427-A1 | Cross-metathesis of olefins directly substituted with an electron-withdrawing group using transition metal carbene catalysts | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-12-25 | — | — | US | disclosed |
| WO-2003087167-A2 | CROSS-METATHESIS OF OLEFINS DIRECTLY SUBSTITUTED WITH AN ELECTRON-WITHDRAWING GROUP USING TRANSITION METAL CARBENE CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2003-10-23 | — | — | WO | disclosed |
| US-6008364-A | Process for producing alkenyl--substituted pyridine derivative | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0891970-A1 | Process for producing alkenylsubstituted pyridine derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1999-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236427-A1 | Cross-metathesis of olefins directly substituted with an electron-withdrawing group using transition metal carbene catalysts | OXER1, DUOX2, AOC2 | NOS3 1321/4885NOS1 1132/4885NOS2 624/4885 |
| US-20250026871-A1 | CYCLIC RUTHENIUM BENZYLIDENE INITIATORS FOR ENHANCED RING EXPANSION METATHESIS POLYMERIZATION | MCM7, MCM4, MCM5 | NOS3 946/4885NOS1 985/4885NOS2 569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.