Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 2/20 | 0.35 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7221116 | 0.88 | NPBWR1 (0.37) | PKMP4HBSMAD3L3MBTL1NPBWR1 | |
| SCHEMBL7221485 | 0.83 | KDM4E (0.37) | PKMP4HBSMAD3L3MBTL1P2RX7 | |
| Hydrochloric Acid SCHEMBL7229127 | 0.83 | KDM4E (0.37) | PKMP4HBSMAD3L3MBTL1NPBWR1 | |
| SCHEMBL7222878 | 0.81 | SMN1; SMN2 (0.46) | POLBALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7221674 | 0.78 | BCL2L1 (0.39) | PKMP4HBSMAD3L3MBTL1NPBWR1 | |
| SCHEMBL7229703 | 0.76 | UGCG (0.39) | HTR1AHTR1DPOLBALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7228986 | 0.76 | UGCG (0.39) | POLBALDH1A1MEN1KMT2AATM | |
| SCHEMBL7223901 | 0.76 | UGCG (0.39) | P2RX7POLBALDH1A1MEN1KMT2A | |
| SCHEMBL7228433 | 0.74 | BCL2L1 (0.41) | L3MBTL1NPBWR1MCHR1ALDH1A1MAPT | |
| SCHEMBL7221784 | 0.73 | LTA4H (0.55) | POLBALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610705-B1 | Treating breast cancer, osteoporosis, hypercholesteremia or endometriosis | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-08-26 | — | — | US | disclosed |