Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7221674 | 0.87 | BCL2L1 (0.39) | BCL2L1BADALDH1A1L3MBTL1LMNA | |
| SCHEMBL7229876 | 0.80 | PKM (0.47) | ALDH1A1L3MBTL1LMNAHPGDATM | |
| Hydrochloric Acid SCHEMBL7221116 | 0.79 | NPBWR1 (0.37) | ALDH1A1L3MBTL1LMNAHPGDATM | |
| SCHEMBL7221784 | 0.78 | LTA4H (0.55) | ALDH1A1LTA4HKMT2AMAPT | |
| SCHEMBL7223602 | 0.78 | MCHR1 (0.46) | ALDH1A1L3MBTL1LTA4HLMNAHPGD | |
| Hydrochloric Acid SCHEMBL7221119 | 0.77 | LTA4H (0.54) | ALDH1A1LTA4HKMT2ATDP1MAPT | |
| SCHEMBL7222876 | 0.74 | PKM (0.36) | ALDH1A1L3MBTL1LMNAHPGDATM | |
| SCHEMBL7222878 | 0.73 | SMN1; SMN2 (0.46) | ALDH1A1LTA4HSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL25446759 | 0.73 | ESR2 (0.64) | ALDH1A1L3MBTL1LTA4HESR2SMN1; SMN2 | |
| SCHEMBL13528449 | 0.73 | ESR2 (0.64) | ALDH1A1L3MBTL1LTA4HESR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610705-B1 | Treating breast cancer, osteoporosis, hypercholesteremia or endometriosis | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-08-26 | — | — | US | disclosed |