Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7224710 | 0.88 | GAA (0.45) | RAB9ANPC1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL7226764 | 0.88 | RAB9A (0.53) | RAB9ANPC1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL7224388 | 0.84 | NPC1 (0.46) | RAB9ANPC1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL7225644 | 0.84 | AKT1 (0.37) | RAB9ANPC1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL7225482 | 0.84 | ALDH1A1 (0.54) | RAB9ANPC1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL7226254 | 0.83 | NPC1 (0.59) | RAB9ANPC1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL7226388 | 0.83 | AKT1 (0.37) | RAB9ANPC1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL375394 | 0.83 | NPC1 (0.44) | RAB9ANPC1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL7074460 | 0.83 | NPC1 (0.44) | RAB9ANPC1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL7234436 | 0.83 | NPC1 (0.45) | RAB9ANPC1L3MBTL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |