Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6289617 | 0.72 | CYP1A2 (0.50) | ALDH1A1NPSR1SMN1; SMN2KDM4ECYP19A1 | |
| SCHEMBL17083048 | 0.68 | GABRA1 (0.52) | KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL6482119 | 0.68 | ALDH1A1 (0.64) | HTTALDH1A1NPSR1SMN1; SMN2KDM4E | |
| SCHEMBL1491086 | 0.66 | CMA1 (0.56) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1USP2 | |
| SCHEMBL3901839 | 0.65 | CA12 (0.61) | HTTALDH1A1SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL6289899 | 0.65 | EDNRB (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8988279 | 0.65 | CA12 (0.51) | MAPTCMA1 | |
| SCHEMBL6289177 | 0.64 | ADORA2A (0.54) | ALDH1A1NPSR1SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL7301245 | 0.64 | TSHR (0.60) | ALDH1A1NPSR1SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL19925941 | 0.63 | POLB (0.50) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6573270-B1 | Endothelin receptor antagonists | PFIZER INC. | 2003-06-03 | — | — | US | disclosed |