Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858690 | 0.84 | CDK9 (0.54) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL7356720 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL31673022 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL30142286 | 0.79 | KMT2A (0.40) | KDM4EKMT2AL3MBTL1MEN1POLB | |
| SCHEMBL20674039 | 0.73 | KDM4E (0.53) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL11482576 | 0.72 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL14158209 | 0.72 | KDM4E (0.38) | KDM4EKMT2AL3MBTL1TSHRHTT | |
| SCHEMBL1596970 | 0.72 | FLT3 (0.64) | KDM4ETSHRHTTSMN1; SMN2CTNNB1 | |
| SCHEMBL28369687 | 0.72 | CHEK1 (0.55) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL11287929 | 0.71 | LMNA (0.52) | KDM4EALDH1A1HPGDGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653304-B2 | Antiarthritic agents; skin disorders; anticarcinogenic agents | BRISTOL-MYERS SQUIBB CO. | 2003-11-25 | — | — | US | disclosed |