Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11855622 | 0.90 | SMN1; SMN2 (0.41) | SMN1; SMN2KMT2AMEN1HTTGALR3 | |
| SCHEMBL7224291 | 0.85 | KMT2A (0.59) | SMN1; SMN2KMT2AMEN1HTTGALR3 | |
| SCHEMBL14263849 | 0.83 | CYP3A4 (0.43) | SMN1; SMN2KMT2AMEN1HTTGALR3 | |
| SCHEMBL10530174 | 0.80 | LMNA (0.57) | SMN1; SMN2KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL30508352 | 0.80 | ALDH1A1 (0.58) | SMN1; SMN2KMT2AMEN1HTTMAPT | |
| SCHEMBL6811979 | 0.80 | ALDH1A1 (0.58) | SMN1; SMN2KMT2AMEN1HTTMAPT | |
| SCHEMBL1285715 | 0.79 | AR (0.44) | SMN1; SMN2HTTMAPTALDH1A1LMNA | |
| SCHEMBL8466527 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL19814165 | 0.78 | ALDH1A1 (0.55) | SMN1; SMN2KMT2AMEN1HTTMAPT | |
| SCHEMBL1270981 | 0.78 | AR (0.43) | SMN1; SMN2KMT2AMEN1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4005199-A | Substituted benzenesulfonamides as anthelmintics | MERCK & CO., INC. (US) | 1977-01-25 | — | — | US | disclosed |
| US-3987199-A | PARASITICIDES | MERCK & CO., INC. (US) | 1976-10-19 | — | — | US | disclosed |