Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.40 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.40 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218234 | 0.86 | L3MBTL1 (0.46) | ALDH1A1LMNAL3MBTL1PDK1PDK2 | |
| SCHEMBL5941054 | 0.84 | NLRP3 (0.56) | ALDH1A1LMNASMN1; SMN2MAPTPOLB | |
| SCHEMBL30502814 | 0.84 | NLRP3 (0.56) | ALDH1A1LMNASMN1; SMN2MAPTPOLB | |
| SCHEMBL7223947 | 0.83 | SMN1; SMN2 (0.49) | ALDH1A1LMNASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL7291906 | 0.83 | ALDH1A1 (0.61) | ALDH1A1LMNASMN1; SMN2L3MBTL1PDK1 | |
| SCHEMBL7217343 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1LMNASMN1; SMN2NPSR1POLB | |
| SCHEMBL7223685 | 0.81 | SMN1; SMN2 (0.50) | ALDH1A1LMNASMN1; SMN2HPGDMAPT | |
| SCHEMBL7224215 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1LMNASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL7225295 | 0.81 | SMN1; SMN2 (0.75) | LMNASMN1; SMN2MAPTTDP1NLRP3 | |
| SCHEMBL27261071 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1LMNASMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |
| US-4300945-A | Synergistic herbicidal compositions | STAUFFER CHEMICAL COMPANY (US) | 1981-11-17 | — | — | US | disclosed |