Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072612 | 0.92 | RAB9A (0.49) | SLC9A1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL7070829 | 0.91 | RAB9A (0.48) | SLC9A1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL7231044 | 0.90 | RAB9A (0.37) | SLC9A1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL7225355 | 0.88 | ALDH1A1 (0.44) | RAB9ASMN1; SMN2HSD17B10KDM4EMAPK1 | |
| SCHEMBL7234830 | 0.84 | RAB9A (0.42) | RAB9ASMN1; SMN2MAPK1NPC1MAPT | |
| SCHEMBL7223815 | 0.84 | GAA (0.37) | RAB9ASMN1; SMN2HSD17B10KDM4EMAPK1 | |
| SCHEMBL7231940 | 0.83 | GAA (0.46) | SLC9A1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL7224710 | 0.83 | GAA (0.45) | SLC9A1RAB9ASMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL7223511 | 0.83 | S1PR2 (0.48) | SLC9A1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL7225840 | 0.83 | RAB9A (0.41) | RAB9ASMN1; SMN2HSD17B10KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |