Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7232158 | 0.90 | ALDH1A1 (0.50) | ALDH1A1KDM4EHSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL7224676 | 0.88 | SLC9A1 (0.45) | ALDH1A1KDM4EHSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL7231044 | 0.86 | RAB9A (0.37) | KDM4EHSD17B10SMN1; SMN2RAB9ASLC6A3 | |
| SCHEMBL7072612 | 0.84 | RAB9A (0.49) | ALDH1A1KDM4EHSD17B10TDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7070829 | 0.83 | RAB9A (0.48) | ALDH1A1KDM4EHSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL7222966 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL7232127 | 0.82 | SLC9A1 (0.48) | ALDH1A1KDM4EHSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL7233102 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KDM4ESMN1; SMN2MAPTRAB9A | |
| SCHEMBL7226523 | 0.81 | SMN1; SMN2 (0.42) | ALDH1A1KDM4EHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL7232458 | 0.81 | HTR4 (0.41) | ALDH1A1KDM4EHSD17B10TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |