Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 18/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7233032 | 0.99 | F10 (0.43) | MEN1GAAHTTRAB9AKMT2A | |
| SCHEMBL7224322 | 0.93 | CHRNA7 (0.40) | MEN1GAAHTTRAB9AKMT2A | |
| SCHEMBL7234416 | 0.90 | F10 (0.37) | MEN1GAAHTTRAB9AKMT2A | |
| SCHEMBL7224323 | 0.90 | MEN1 (0.38) | MEN1GAAHTTRAB9AKMT2A | |
| SCHEMBL7223199 | 0.84 | HDAC6 (0.40) | RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL7071352 | 0.84 | ALDH1A1 (0.55) | MEN1GAAHTTRAB9AKMT2A | |
| SCHEMBL7225002 | 0.84 | ALDH1A1 (0.55) | MEN1GAAHTTRAB9AKMT2A | |
| SCHEMBL7223510 | 0.84 | NPC1 (0.52) | MEN1RAB9AKMT2AF10 | |
| SCHEMBL7231972 | 0.83 | ESRRG (0.46) | — | |
| Hydrochloric Acid SCHEMBL7232683 | 0.83 | ALDH1A1 (0.53) | MEN1GAAHTTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |