Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 6/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19048790 | 0.87 | LMNA (0.36) | LMNAMAOAHDAC1HDAC2HDAC8 | |
| SCHEMBL16774420 | 0.87 | ALDH1A1 (0.36) | LMNAMAOAHDAC1HDAC2HDAC8 | |
| SCHEMBL7253923 | 0.84 | LMNA (0.36) | LMNAMAOAHDAC1HDAC2HDAC8 | |
| SCHEMBL7249853 | 0.83 | POLB (0.44) | LMNATSHRMAPT | |
| SCHEMBL17197232 | 0.81 | LMNA (0.41) | LMNAMAOAHDAC1HDAC2HDAC8 | |
| SCHEMBL8982258 | 0.78 | NPC1 (0.46) | LMNAMAOAHDAC1HDAC2HDAC8 | |
| SCHEMBL8998078 | 0.78 | CYP2B6 (0.44) | LMNAMAOAHDAC1HDAC2HDAC8 | |
| SCHEMBL16774399 | 0.77 | DHODH (0.45) | LMNAMAOAHDAC1HDAC2HDAC8 | |
| SCHEMBL16774378 | 0.77 | PGK1 (0.41) | LMNAMAOAHDAC1HDAC2HDAC8 | |
| SCHEMBL16774525 | 0.76 | PGK1 (0.39) | LMNAMAOAHDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6639070-B1 | 4-substituted 1,3,4-oxadiazines; herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2003-10-28 | — | — | US | disclosed |
| US-6525000-B1 | N-aminoureas are reacted with formaldehyde to give methyleneimino ureas, cyclizing these to give tetrahydro-4H-1,3,4-oxa(or thia)diazines, and cyclizing the fused triazoles using phosgene; herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-25 | — | — | US | disclosed |