Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.58 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PLEC | Q15149 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3440911 | 0.85 | PRKCI (0.61) | PRKCIPTGER4GAAKDM4EALDH1A1 | |
| SCHEMBL22931144 | 0.82 | PTGER4 (0.71) | PTGER4GAAKDM4EALDH1A1MAPT | |
| SCHEMBL5591978 | 0.82 | HPGD (0.48) | PTGER4GAAKDM4EALDH1A1MAPT | |
| SCHEMBL2082009 | 0.80 | KDM4E (0.76) | PRKCIPTGER4GAAKDM4EALDH1A1 | |
| SCHEMBL14457852 | 0.79 | SMN1; SMN2 (0.54) | PRKCIPTGER4GAAKDM4EALDH1A1 | |
| SCHEMBL5104664 | 0.79 | PTGER4 (0.43) | PRKCIPTGER4GAAKDM4EALDH1A1 | |
| SCHEMBL11542994 | 0.78 | PRKCI (0.60) | PRKCIPTGER4GAAKDM4EALDH1A1 | |
| SCHEMBL7230677 | 0.78 | HCAR3 (0.59) | PTGER4ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5591721 | 0.78 | PTGER4 (0.39) | PRKCIPTGER4GAAKDM4EALDH1A1 | |
| SCHEMBL5591910 | 0.77 | L3MBTL1 (0.45) | PTGER4GAAKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506738-B1 | Treatment of viral infections. More particularly, the invention provides benzimidazolone derivatives for the treatment of respiratory syncytial virus infection. | BRISTOL-MYERS SQUIBB COMPANY | 2003-01-14 | — | — | US | disclosed |
| WO-2002026228-A1 | BENZIMIDAZOLONE ANTIVIRAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-04-04 | — | — | WO | disclosed |