Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 10/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3440916 | 0.86 | HCAR3 (0.57) | HCAR3MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL5591690 | 0.84 | HCAR3 (0.56) | HCAR3MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL14106643 | 0.84 | PRSS1 (0.55) | HCAR3MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL11267808 | 0.83 | HCAR3 (0.81) | HCAR3MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL14457839 | 0.82 | MAPT (0.53) | HCAR3MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL5092011 | 0.81 | HCAR3 (0.50) | HCAR3MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL11543635 | 0.81 | HCAR3 (0.57) | HCAR3MAPTALDH1A1RAB9ANPC1 | |
| Methane SCHEMBL27449377 | 0.81 | MAPT (0.54) | HCAR3MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL5591726 | 0.80 | ALDH1A1 (0.50) | HCAR3MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL6215124 | 0.80 | KAT2B (0.47) | HCAR3MAPTALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506738-B1 | Treatment of viral infections. More particularly, the invention provides benzimidazolone derivatives for the treatment of respiratory syncytial virus infection. | BRISTOL-MYERS SQUIBB COMPANY | 2003-01-14 | — | — | US | disclosed |
| WO-2002026228-A1 | BENZIMIDAZOLONE ANTIVIRAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-04-04 | — | — | WO | disclosed |