Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2973753 | 0.88 | BACE1 (0.49) | ALDH1A1KDM4EBACE1CYP1A2CYP3A4 | |
| SCHEMBL27882729 | 0.85 | LMNA (0.46) | ALDH1A1KDM4ECYP1A2LMNATDP1 | |
| SCHEMBL27541524 | 0.83 | CYP1A2 (0.46) | ALDH1A1KDM4ECYP1A2LMNATDP1 | |
| SCHEMBL987189 | 0.83 | TDP1 (0.62) | ALDH1A1KDM4ECYP1A2LMNATDP1 | |
| SCHEMBL23151971 | 0.81 | LMNA (0.43) | ALDH1A1KDM4ECYP1A2LMNATDP1 | |
| SCHEMBL28773734 | 0.81 | SIRT6 (0.53) | ALDH1A1KDM4ECYP1A2LMNATDP1 | |
| SCHEMBL19623132 | 0.81 | GRM5 (0.51) | ALDH1A1KDM4EBACE1CYP3A4HPGD | |
| SCHEMBL17477633 | 0.81 | CYP3A4 (0.46) | ALDH1A1KDM4EBACE1CYP1A2CYP3A4 | |
| SCHEMBL30743068 | 0.81 | LMNA (0.43) | ALDH1A1KDM4ECYP1A2LMNATDP1 | |
| SCHEMBL30418230 | 0.81 | CYP3A4 (0.46) | ALDH1A1KDM4EBACE1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610853-B1 | N-(phenylsulfonyl)picolinamide derivatives, process for producing the same, and herbicide | KUREHA KAGAKU KOGYO K.K. (JP) | 2003-08-26 | — | — | US | disclosed |
| EP-1069112-A1 | N-(PHENYLSULFONYL) PICOLINAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-01-17 | — | — | EP | disclosed |