Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL746177 | 0.88 | TDP1 (0.55) | TDP1LMNAKDM4EALDH1A1ALOX15 | |
| SCHEMBL27882729 | 0.86 | LMNA (0.46) | TDP1LMNAKDM4EALDH1A1SIRT6 | |
| SCHEMBL794917 | 0.86 | TDP1 (0.53) | TDP1LMNAKDM4EALDH1A1ALOX15 | |
| SCHEMBL27541524 | 0.85 | CYP1A2 (0.46) | TDP1LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL23151971 | 0.83 | LMNA (0.43) | TDP1LMNAKDM4EALDH1A1SIRT6 | |
| SCHEMBL7225274 | 0.83 | ALDH1A1 (0.56) | TDP1LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL1424927 | 0.83 | LMNA (0.51) | TDP1LMNAKDM4EALDH1A1ALOX15 | |
| SCHEMBL28773734 | 0.83 | SIRT6 (0.53) | TDP1LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL30743068 | 0.83 | LMNA (0.43) | TDP1LMNAKDM4EALDH1A1SIRT6 | |
| SCHEMBL3401912 | 0.81 | ALDH1A1 (0.56) | TDP1LMNAKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641854-A | Integration stress access regulator | 卡里科生命科学有限责任公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-102164894-A | Heteroaryl antagonists of prostaglandin D2 receptors | AMIRA PHARMACEUTICALS INC | 2011-08-24 | — | — | CN | disclosed |
| US-7875631-B2 | e.g.1-(3,5-dichlorophenyl)-2-formyl-6-methoxy-1,2,3,4-tetrahydroisoquinoline; to prevent and/or treat cancer and other abnormal cell growth, and metabolic as well as blood vessel proliferate disorders, in which uncontrolled expression of insulin-like growth factor-1 receptor is observed | ANALYTECON S.A. (CH) | 2011-01-25 | — | — | US | disclosed |
| US-6610853-B1 | N-(phenylsulfonyl)picolinamide derivatives, process for producing the same, and herbicide | KUREHA KAGAKU KOGYO K.K. (JP) | 2003-08-26 | — | — | US | disclosed |
| EP-1069112-A1 | N-(PHENYLSULFONYL) PICOLINAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-01-17 | — | — | EP | disclosed |
| CN-1042729-C | N-sulfonyl carboxylic amide derivative incluoding an N-containing 6-member aromatic ring, or the salf of the game, method for producting the same, and pesticide including herbicide | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-03-31 | — | — | CN | disclosed |
| CN-1077950-A | The nitrogenous 6 Yuans aromatic nucleus carboxylic acid amide derivatives of N-alkylsulfonyl and salt and noxious organism control agent | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1993-11-03 | — | — | CN | disclosed |