Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29150894 | 0.80 | ELANE (0.47) | MEN1KMT2AELANEL3MBTL1KDM4E | |
| SCHEMBL1308058 | 0.77 | KMT2A (0.59) | MEN1KMT2AELANEL3MBTL1KDM4E | |
| SCHEMBL6026809 | 0.77 | MEN1 (0.55) | MEN1KMT2AELANEL3MBTL1KDM4E | |
| SCHEMBL6026933 | 0.76 | ELANE (0.68) | MEN1KMT2AELANEL3MBTL1SMN1; SMN2 | |
| SCHEMBL11227804 | 0.75 | KMT2A (0.58) | MEN1KMT2AELANEL3MBTL1KDM4E | |
| SCHEMBL6027054 | 0.74 | MEN1 (0.44) | MEN1KMT2AELANEL3MBTL1KDM4E | |
| SCHEMBL6027149 | 0.74 | SERPINE1 (0.46) | MEN1KMT2AELANEL3MBTL1KDM4E | |
| SCHEMBL17292472 | 0.73 | LMNA (0.52) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL6027161 | 0.73 | ELANE (0.46) | MEN1KMT2AELANEL3MBTL1KDM4E | |
| SCHEMBL7101491 | 0.73 | MEN1 (0.43) | MEN1KMT2AELANEL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143062-B | 4-Hydroxy-2-pyrone compound, preparation method and application | 西北农林科技大学 | 2024-09-20 | — | — | CN | disclosed |
| CN-117143062-A | 3-substituted 4-hydroxy-2-pyrone compound, preparation method and application | 西北农林科技大学 | 2023-12-01 | — | — | CN | disclosed |
| US-6509298-B2 | A 4-hydroxy-6-methyl-3-(3-methylbutanoyl)-2-pyrone; insecticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-01-21 | — | — | US | disclosed |
| US-20020173541-A1 | Arthropod-controlling composition | SUMITOMO CHEMICAL COMPANY, LIMITED | 2002-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173541-A1 | Arthropod-controlling composition | DDT, HMGCR, CYP4B1 | MEN1 2243/4885KMT2A 480/4885ELANE 2397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.