Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207260 | 0.83 | CYP3A4 (0.45) | MAPTMEN1KMT2ACYP3A4PDE10A | |
| SCHEMBL7225962 | 0.82 | ADORA2A (0.57) | NPC1MEN1KMT2AADORA2AADORA1 | |
| SCHEMBL15212407 | 0.81 | ACP1 (0.56) | MAPTNPC1TACR3LMNAALDH1A1 | |
| SCHEMBL7208784 | 0.80 | MAPT (0.49) | MAPTTACR3ADORA2AADORA1RECQL | |
| SCHEMBL7212295 | 0.76 | ADORA2A (0.69) | MAPTTACR3KMT2AADORA2AADORA1 | |
| SCHEMBL16307497 | 0.76 | KDM4E (0.49) | MAPTNPC1TACR3MEN1KMT2A | |
| SCHEMBL16019540 | 0.75 | BCL2L1 (0.47) | MAPTNPC1MEN1KMT2AHTR3E | |
| SCHEMBL14424722 | 0.75 | MAPT (0.56) | MAPTNPC1MEN1KMT2ACYP3A4 | |
| SCHEMBL14424717 | 0.75 | MAPT (0.56) | MAPTNPC1MEN1KMT2ACYP3A4 | |
| SCHEMBL7221180 | 0.74 | ADORA2A (0.43) | NPC1TACR3MEN1KMT2AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583156-B1 | Particularly adenosine A2A receptors; neurodegenerative disorders; 2,8-bis(trifluoromethyl)-alpha -(3-thienyl)-4-quinolinemethanol | VERNALIS RESEARCH LIMITED (GB) | 2003-06-24 | — | — | US | disclosed |