Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7230430 | 0.90 | RAB9A (0.41) | SLC9A1NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL7234393 | 0.89 | SLC9A1 (0.45) | SLC9A1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL7233285 | 0.89 | MMP13 (0.48) | NPC1RAB9AKMT2AALDH1A1HPGD | |
| SCHEMBL7231745 | 0.88 | MAPT (0.44) | NPC1RAB9AALDH1A1HPGDTSHR | |
| SCHEMBL7232692 | 0.88 | NPC1 (0.42) | NPC1RAB9AKMT2AALDH1A1HPGD | |
| SCHEMBL7224791 | 0.88 | NPC1 (0.44) | NPC1RAB9AKMT2AALDH1A1HPGD | |
| SCHEMBL7224154 | 0.87 | NPC1 (0.42) | NPC1RAB9AKMT2AALDH1A1HPGD | |
| SCHEMBL7231970 | 0.87 | MAPT (0.46) | NPC1RAB9AKMT2AALDH1A1TSHR | |
| SCHEMBL7223990 | 0.87 | RAB9A (0.42) | NPC1RAB9AKMT2AALDH1A1HPGD | |
| SCHEMBL7223992 | 0.87 | RAB9A (0.42) | NPC1RAB9AKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |