Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF3 | O95398 | 5/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GALK1 | P51570 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7226446 | 1.00 | RAPGEF3 (0.39) | RAPGEF3RAPGEF4MEN1KMT2AKIF11 | |
| SCHEMBL7066568 | 0.83 | LMNA (0.40) | MEN1KMT2AMAPTKCNK3KCNK9 | |
| SCHEMBL7066549 | 0.83 | MGLL (0.45) | MEN1KMT2AMAPTKCNK3KCNK9 | |
| SCHEMBL7066546 | 0.83 | MGLL (0.45) | MEN1KMT2AMAPTKCNK3KCNK9 | |
| SCHEMBL7066566 | 0.83 | LMNA (0.40) | MEN1KMT2AMAPTKCNK3KCNK9 | |
| SCHEMBL6078210 | 0.77 | MEN1 (0.38) | MEN1KMT2AKIF11NR1H4GRIA2 | |
| SCHEMBL6078207 | 0.77 | MEN1 (0.38) | MEN1KMT2AKIF11NR1H4GRIA2 | |
| SCHEMBL7235541 | 0.77 | MEN1 (0.37) | RAPGEF3RAPGEF4MEN1KMT2ANR1H4 | |
| SCHEMBL7235547 | 0.77 | MEN1 (0.37) | RAPGEF3RAPGEF4MEN1KMT2ANR1H4 | |
| SCHEMBL7226461 | 0.75 | EPHX2 (0.36) | RAPGEF3RAPGEF4MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624179-B1 | Analyzed by reversed phase liquid chromatography in which a packing comprising silica having chemically bonded thereto an alkyl group selected from trimethyl, octyl and octadecyl, is used as the stationary phase, and a polar solvent selected | ISHIHARA SANGYO KAISHA LTD. (JP) | 2003-09-23 | — | — | US | disclosed |
| EP-1201646-A1 | GEOMETRICAL ISOMER OF ACRYLONITRILE COMPOUND, MIXTURE THEREOF, AND PROCESS FOR PRODUCING THESE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2002-05-02 | — | — | EP | disclosed |