Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.59 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 9/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7228297 | 0.96 | MCHR1 (0.64) | MCHR1FAAHACHE | |
| Hydrochloric Acid SCHEMBL8146755 | 0.95 | MCHR1 (0.63) | MCHR1FAAHACHE | |
| Hydrochloric Acid SCHEMBL7236259 | 0.94 | MCHR1 (0.55) | MCHR1ACHE | |
| SCHEMBL7226780 | 0.93 | FAAH (0.59) | MCHR1FAAHACHE | |
| Hydrochloric Acid SCHEMBL7236249 | 0.93 | FAAH (0.58) | MCHR1FAAHACHE | |
| SCHEMBL7227479 | 0.90 | MCHR1 (0.51) | MCHR1FAAHACHE | |
| SCHEMBL7234946 | 0.88 | ACHE (0.60) | MCHR1FAAHACHE | |
| Hydrochloric Acid SCHEMBL7227310 | 0.88 | ACHE (0.62) | FAAHACHE | |
| Hydrochloric Acid SCHEMBL7227488 | 0.88 | ACHE (0.62) | FAAHACHE | |
| SCHEMBL7236253 | 0.88 | FAAH (0.54) | MCHR1FAAHACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534496-B1 | Prophylactic and/or therapeutic drug for obesity and obesity associated diseasestor diabetes with a reduced risk for central side effects and high universality in usage. Another object of the a lipolytic agent, or a prophylactic and/or | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-0975624-A1 | THERMOGENIC COMPOSITION AND BENZAZEPINE THERMOGENICS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046590-A1 | THERMOGENIC COMPOSITION AND BENZAZEPINE THERMOGENICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-22 | — | — | WO | disclosed |