Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 19/20 | 0.48 |
| ▸ | ITGAV | P06756 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7229611 | 0.96 | ITGB3 (0.46) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7229556 | 0.94 | ITGB3 (0.42) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7237720 | 0.93 | ITGB3 (0.44) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7237989 | 0.90 | ITGB3 (0.46) | ITGB3ITGA2BITGAVPTPN1 | |
| SCHEMBL7229449 | 0.90 | ITGB3 (0.57) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7237738 | 0.90 | ITGB3 (0.40) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7230083 | 0.89 | ITGB3 (0.44) | ITGB3ITGA2BITGAVPTPN1 | |
| SCHEMBL7230723 | 0.88 | ITGB3 (0.42) | ITGB3ITGA2BITGAVPTPN1 | |
| SCHEMBL7238373 | 0.88 | ITGB3 (0.43) | ITGB3ITGA2BITGAVPTPN1 | |
| SCHEMBL7235817 | 0.87 | YAP1 (0.39) | ITGB3ITGA2BITGAVCHRM2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602876-B1 | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2003-08-05 | — | — | US | disclosed |
| US-6204280-B1 | OXAZOLIDINONE DERIVATIVE, ANTICOAGULANT | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKTER HAFTUNG (DE) | 2001-03-20 | — | — | US | disclosed |
| EP-0710657-B1 | Antagonists of adhesion receptors | MERCK PATENT GMBH (DE) | 1998-08-26 | — | — | EP | disclosed |
| EP-0710657-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-08 | — | — | EP | disclosed |