Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | FKBP5 | Q13451 | 3/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220712 | 0.80 | L3MBTL1 (0.61) | FKBP5FKBP1AL3MBTL1SMN1; SMN2HSD17B10 | |
| SCHEMBL7221488 | 0.80 | L3MBTL1 (0.61) | FKBP5FKBP1AL3MBTL1SMN1; SMN2HSD17B10 | |
| SCHEMBL7220717 | 0.80 | L3MBTL1 (0.61) | FKBP5FKBP1AL3MBTL1SMN1; SMN2HSD17B10 | |
| SCHEMBL7221476 | 0.80 | L3MBTL1 (0.61) | FKBP5FKBP1AL3MBTL1SMN1; SMN2HSD17B10 | |
| SCHEMBL7506812 | 0.73 | FKBP1A (0.59) | FKBP1AL3MBTL1 | |
| SCHEMBL7220517 | 0.73 | FKBP1A (0.59) | FKBP1AL3MBTL1 | |
| SCHEMBL7220384 | 0.71 | FKBP1A (0.69) | FKBP1A | |
| SCHEMBL7507953 | 0.71 | FKBP1A (0.69) | FKBP1A | |
| SCHEMBL9129230 | 0.71 | SLC29A1 (0.71) | SLC29A1ATMSMN1; SMN2DRD2ADRA1A | |
| SCHEMBL7504251 | 0.70 | FKBP1A (0.66) | FKBP5FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6544987-B2 | Pyrrolidine or piperidine sulfonyl compounds; stimulate neurite outgrowth in nerve cells leading to nerve regeneration for treatment of hair loss, memory loss or vision disorders | PFIZER INC. | 2003-04-08 | — | — | US | disclosed |