Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 1.00 |
| ▸ | MAOB | P27338 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235850 | 0.82 | MAOA (0.70) | MAOAMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL7235146 | 0.78 | MAOA (0.64) | MAOAMAOBMEN1KMT2ALMNA | |
| SCHEMBL7230184 | 0.77 | MAOA (0.62) | MAOAMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL7228612 | 0.76 | MAOA (0.61) | MAOAMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL7238812 | 0.76 | MAOA (0.61) | MAOAMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL24163549 | 0.75 | SMN1; SMN2 (0.73) | MAOAMAOBLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL7394086 | 0.75 | SMN1; SMN2 (0.73) | MAOAMAOBLMNAKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7401914 | 0.74 | SMN1; SMN2 (0.71) | MAOAMAOBLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5480294 | 0.74 | HPGD (0.61) | MAOAMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL7228164 | 0.73 | MAOA (0.57) | MAOAMAOBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6649623-B1 | Administering tetrahydropiperidine derivative; antidiabetic agents; hyperlipemia treatment; hypotensive agents | SHIONOGI & CO., LTD. (JP) | 2003-11-18 | — | — | US | disclosed |
| EP-1151993-A1 | CYCLIC AMINE DERIVATIVES AND USES THEREOF | SHIONOGI & CO., LTD. (JP) | 2001-11-07 | — | — | EP | disclosed |