Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | CPT1A | P50416 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7223958 | 0.86 | NPSR1 (0.34) | CYP2C19GRM5RIPK2GAA | |
| SCHEMBL7223294 | 0.82 | GRM5 (0.33) | GRM5RIPK2 | |
| SCHEMBL7985946 | 0.82 | RIPK2 (0.32) | GRM5RIPK2 | |
| SCHEMBL7228279 | 0.82 | GRM5 (0.33) | GRM5RIPK2 | |
| SCHEMBL7696111 | 0.82 | GRM5 (0.37) | GRM5RIPK2 | |
| SCHEMBL7952198 | 0.79 | GRM5 (0.41) | GRM5RIPK2GAA | |
| SCHEMBL7223856 | 0.79 | CYP11B2 (0.35) | CYP2C19GRM5RIPK2 | |
| SCHEMBL7697700 | 0.78 | GRM5 (0.41) | GRM5RIPK2GAA | |
| SCHEMBL7221991 | 0.77 | NPSR1 (0.47) | CYP2C19GRM5ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7228283 | 0.76 | RIPK2 (0.33) | RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6573275-B1 | Insecticidal compositions comprising and to methods of combatting and controlling insect pests therewith. | SYNGENTA LIMITED (GB) | 2003-06-03 | — | — | US | disclosed |
| EP-0828739-B1 | BICYCLIC AMINES AS INSECTICIDES | SYNGENTA LTD (GB) | 2002-09-11 | — | — | EP | disclosed |
| US-6391883-B1 | INSECTICIDES | SYNGENTA LIMITED (GB) | 2002-05-21 | — | — | US | disclosed |
| US-6207676-B1 | Bicyclic amines | ZENECA LIMITED (GB) | 2001-03-27 | — | — | US | disclosed |
| EP-0828739-A1 | BICYCLIC AMINES AS INSECTICIDES | ZENECA LIMITED (GB) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037494-A1 | BICYCLIC AMINES AS INSECTICIDES | ZENECA LIMITED (GB) | 1996-11-28 | — | — | WO | disclosed |