Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | KRAS | P01116 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7228279 | 0.90 | GRM5 (0.33) | GRM5NPSR1RIPK2 | |
| SCHEMBL7223958 | 0.88 | NPSR1 (0.34) | GRM5NPSR1RIPK2 | |
| SCHEMBL7223294 | 0.88 | GRM5 (0.33) | GRM5NPSR1RIPK2 | |
| SCHEMBL7985946 | 0.88 | RIPK2 (0.32) | GRM5NPSR1RIPK2 | |
| SCHEMBL7223856 | 0.84 | CYP11B2 (0.35) | GRM5NPSR1RIPK2CYP11B1CYP11B2 | |
| SCHEMBL16115912 | 0.83 | GPR119 (0.43) | GRM5GPR119 | |
| SCHEMBL17507199 | 0.83 | GPR119 (0.43) | GRM5GPR119 | |
| SCHEMBL17507200 | 0.83 | GPR119 (0.43) | GRM5GPR119 | |
| SCHEMBL7221991 | 0.82 | NPSR1 (0.47) | GRM5NPSR1 | |
| SCHEMBL7228357 | 0.82 | CYP2C9 (0.38) | GRM5RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057262-A2 | BICYCLIC AMINES AS INSECTICIDES | SYNGENTA LIMITED (GB) | 2002-07-25 | — | — | WO | disclosed |