Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 10/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 7/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219819 | 0.93 | CRHR1 (0.43) | CRHR1RAD52CD38KDM4EMEN1 | |
| SCHEMBL7219519 | 0.91 | CRHR1 (0.37) | CRHR1CD38KDM4EMEN1KMT2A | |
| SCHEMBL7220635 | 0.74 | CRHR1 (0.41) | CRHR1CD38 | |
| SCHEMBL7222858 | 0.74 | CRHR1 (0.35) | CRHR1 | |
| SCHEMBL7226595 | 0.74 | CRHR1 (0.51) | CRHR1KDM4EMEN1KMT2A | |
| SCHEMBL7220332 | 0.67 | CRHR1 (0.49) | CRHR1CD38KDM4ECYP3A4 | |
| SCHEMBL7221799 | 0.67 | CRHR1 (0.48) | CRHR1CD38MEN1KMT2ACYP3A4 | |
| SCHEMBL7219466 | 0.67 | CRHR1 (0.40) | CRHR1CD38KDM4EMEN1KMT2A | |
| SCHEMBL7219475 | 0.65 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL5599486 | 0.64 | CRHR1 (0.48) | CRHR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103553-A2 | Substituted heterocyclic derivatives | Pfizer Products Inc. (US) | 2001-05-30 | — | — | EP | claimed |
| US-6525067-B1 | Corticotropin releasing factor antagonists; such as 1-(2-methyl-8-(2,4,6-trimethyl-phenyl)-quinolin-4-yl)-propan-1-one-oxime | PFIZER INC | 2003-02-25 | — | — | US | disclosed |
| EP-1103553-A2 | Substituted heterocyclic derivatives | Pfizer Products Inc. (US) | 2001-05-30 | — | — | EP | disclosed |