Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140230 | 0.87 | THRA (0.53) | THRATHRB | |
| SCHEMBL7232341 | 0.85 | THRA (0.59) | THRATHRB | |
| SCHEMBL7133145 | 0.85 | THRA (0.60) | THRATHRB | |
| SCHEMBL7231405 | 0.80 | THRA (0.35) | THRATHRB | |
| SCHEMBL7131426 | 0.80 | GSK3B (0.37) | THRATHRB | |
| SCHEMBL7225729 | 0.79 | THRA (0.53) | THRATHRB | |
| SCHEMBL7130895 | 0.78 | THRA (0.66) | THRATHRB | |
| SCHEMBL7129345 | 0.78 | CNR2 (0.40) | THRATHRB | |
| SCHEMBL7088287 | 0.76 | THRA (0.78) | THRATHRB | |
| SCHEMBL7135874 | 0.76 | THRA (0.73) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608049-B2 | Indazoles | BAYER AKTIENGESELLSCHAFT (DE) | 2003-08-19 | — | — | US | disclosed |
| US-20020193610-A1 | Indazoles | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193610-A1 | Indazoles | CYP3A43, CYP3A5, CYP3A4 | THRA 3910/4885THRB 4025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.