Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GCGR | P47871 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652406 | 0.81 | GCGR (0.61) | KDM4EALDH1A1MAPTABCB1MEN1 | |
| SCHEMBL9072180 | 0.78 | GCGR (0.77) | GCGR | |
| SCHEMBL7229718 | 0.73 | GCGR (0.66) | KDM4EALDH1A1MAPTABCB1MEN1 | |
| SCHEMBL3860629 | 0.72 | KDM4E (0.69) | KDM4EALDH1A1MAPTABCB1MEN1 | |
| SCHEMBL2664373 | 0.71 | ABCB1 (0.54) | KDM4EALDH1A1MAPTABCB1MEN1 | |
| SCHEMBL7239058 | 0.71 | KDM4E (0.54) | KDM4EALDH1A1MAPTABCB1MEN1 | |
| SCHEMBL7333842 | 0.69 | L3MBTL1 (0.54) | KDM4EALDH1A1MAPTABCB1MEN1 | |
| SCHEMBL2650140 | 0.69 | GCGR (0.59) | KDM4EALDH1A1MAPTABCB1MEN1 | |
| SCHEMBL5833752 | 0.67 | NOS3 (0.74) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8501315 | 0.67 | SIGMAR1 (0.68) | KDM4EABCB1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |