Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7229906 | 0.94 | XDH (0.52) | XDHMAOAACHEBCHEMAPT | |
| SCHEMBL7238515 | 0.89 | MAOA (0.50) | XDHMAOAACHEBCHEMAPT | |
| SCHEMBL7237933 | 0.89 | MAOA (0.52) | XDHMAOAACHEBCHEMAPT | |
| SCHEMBL5748445 | 0.85 | MAOA (0.58) | XDHMAOAACHEBCHEMAPT | |
| SCHEMBL5798486 | 0.84 | XDH (0.65) | XDHMAOAACHEBCHEMAPT | |
| SCHEMBL7381861 | 0.82 | XDH (0.60) | XDHMAOAACHEBCHEMAPT | |
| SCHEMBL7425703 | 0.82 | XDH (0.60) | XDHMAOAACHEBCHEMAPT | |
| SCHEMBL5747126 | 0.78 | MAOA (0.57) | XDHMAOAACHEBCHECYP2A6 | |
| SCHEMBL5746390 | 0.77 | MAOA (0.56) | XDHMAOAACHEBCHECYP2A6 | |
| SCHEMBL5745354 | 0.76 | MAOA (0.61) | XDHMAOAACHEBCHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613797-B2 | New xanthone derivatives useful for treating protozoan diseases | INTERLAB, INC. | 2003-09-02 | — | — | US | disclosed |