Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22296973 | 1.00 | EPHX1 (0.71) | EPHX1HTTMEN1THRBKMT2A | |
| SCHEMBL20548046 | 1.00 | EPHX1 (0.71) | EPHX1HTTMEN1THRBKMT2A | |
| SCHEMBL15279667 | 1.00 | EPHX1 (0.71) | EPHX1HTTMEN1THRBKMT2A | |
| SCHEMBL8979926 | 0.98 | EPHX1 (0.67) | EPHX1HTTMEN1THRBKMT2A | |
| SCHEMBL23342876 | 0.95 | EPHX1 (0.64) | EPHX1HTTMEN1THRBKMT2A | |
| SCHEMBL8979942 | 0.95 | EPHX1 (0.64) | EPHX1HTTMEN1THRBKMT2A | |
| SCHEMBL15510919 | 0.95 | EPHX1 (0.64) | EPHX1HTTMEN1THRBKMT2A | |
| SCHEMBL15511002 | 0.95 | EPHX1 (0.64) | EPHX1HTTMEN1THRBKMT2A | |
| SCHEMBL14051928 | 0.95 | EPHX1 (0.64) | EPHX1HTTMEN1THRBKMT2A | |
| SCHEMBL2599824 | 0.93 | EPHX1 (0.59) | EPHX1HTTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111053706-A | Self-heating pre-wash hair care composition | 澳宝化妆品（惠州）有限公司 | 2020-04-24 | — | — | CN | disclosed |
| EP-2404592-B1 | HAIR TREATMENT COMPOSITION | SHISEIDO CO LTD (JP) | 2018-07-18 | — | — | EP | disclosed |
| US-8273336-B2 | Hair treatment composition | SHISEIDO COMPANY, LTD. (JP) | 2012-09-25 | — | — | US | disclosed |
| US-20120052032-A1 | HAIR TREATMENT COMPOSITION | SHISEIDO COMPANY, LTD. (JP) | 2012-03-01 | — | — | US | disclosed |
| EP-2404592-A1 | HAIR TREATMENT COMPOSITION | Shiseido Company, Ltd. (JP) | 2012-01-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052032-A1 | HAIR TREATMENT COMPOSITION | POLR1C, SHH, DNMT1 | EPHX1 4112/4885HTT 608/4885MEN1 2207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.