SCHEMBL7229717

SCHEMBL7229717

CCN(CC)c1ccc(N=Nc2ncc(Cl)cc2Cl)c(O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.43
KCNH2 Q12809 4/20 0.39
MAPT P10636 10/20 0.39
ALDH1A1 P00352 9/20 0.39
RAB9A P51151 5/20 0.39
PLAU P00749 1/20 0.38
SMN1; SMN2 Q16637 5/20 0.38
LMNA P02545 4/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 6/20 0.38
MEN1 O00255 4/20 0.38
TDP1 Q9NUW8 2/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
NPC1 O15118 3/20 0.37
GAA P10253 2/20 0.36
HTT P42858 2/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7229713 1.00 KMT2A (0.43) KMT2AKCNH2MAPTALDH1A1RAB9A
SCHEMBL7228523 0.87 PLAU (0.44) KMT2AKCNH2MAPTALDH1A1RAB9A
SCHEMBL7228528 0.87 PLAU (0.44) KMT2AKCNH2MAPTALDH1A1RAB9A
SCHEMBL8654656 0.82 KCNH2 (0.47) KMT2AKCNH2MAPTALDH1A1RAB9A
SCHEMBL8654659 0.82 KCNH2 (0.47) KMT2AKCNH2MAPTALDH1A1RAB9A
SCHEMBL13662909 0.81 MAPT (0.45) KMT2AKCNH2MAPTALDH1A1RAB9A
SCHEMBL8651528 0.79 KCNH2 (0.38) KMT2AKCNH2MAPTALDH1A1RAB9A
SCHEMBL8651527 0.79 KCNH2 (0.38) KMT2AKCNH2MAPTALDH1A1RAB9A
SCHEMBL13662903 0.78 L3MBTL1 (0.48) KMT2AKCNH2MAPTALDH1A1RAB9A
SCHEMBL13531277 0.74 KCNH2 (0.40) KMT2AKCNH2MAPTALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6551682-B1 Proper tracking error signals to be adapted to high density information recording and has various characteristics MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2003-04-22 US disclosed