SCHEMBL13662909

SCHEMBL13662909

CCN(CC)c1ccc(N=Nc2ccc(Cl)cc2O)c(O)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 14/20 0.45
ALDH1A1 P00352 13/20 0.45
RAB9A P51151 3/20 0.45
KMT2A Q03164 6/20 0.44
KDM4E B2RXH2 6/20 0.44
MEN1 O00255 5/20 0.44
LMNA P02545 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44
GAA P10253 7/20 0.44
MAPK1 P28482 2/20 0.44
NPC1 O15118 2/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
HTT P42858 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
NPSR1 Q6W5P4 2/20 0.42
BLM P54132 1/20 0.42
THRB P10828 1/20 0.42
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13662903 0.93 L3MBTL1 (0.48) MAPTALDH1A1RAB9AKMT2AKDM4E
SCHEMBL13662912 0.85 NR1H2 (0.48) MAPTALDH1A1RAB9AKMT2AKDM4E
SCHEMBL8654656 0.84 KCNH2 (0.47) MAPTALDH1A1RAB9AKMT2AKDM4E
SCHEMBL8654659 0.84 KCNH2 (0.47) MAPTALDH1A1RAB9AKMT2AKDM4E
SCHEMBL13662908 0.82 KCNH2 (0.56) MAPTALDH1A1KMT2AMEN1TDP1
SCHEMBL7229717 0.81 KMT2A (0.43) MAPTALDH1A1RAB9AKMT2AKDM4E
SCHEMBL7229713 0.81 KMT2A (0.43) MAPTALDH1A1RAB9AKMT2AKDM4E
SCHEMBL13662904 0.79 NR1H2 (0.48) MAPTALDH1A1RAB9AKMT2AKDM4E
SCHEMBL13662907 0.78 ALDH1A1 (0.50) MAPTALDH1A1RAB9AKMT2AKDM4E
SCHEMBL374911 0.77 MAPT (0.53) MAPTALDH1A1RAB9AKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090269543-A1 OPTICAL RECORDING MEDIUM TDK CORPORATION (JP) 2009-10-29 US disclosed
US-20090269543-A1 OPTICAL RECORDING MEDIUM TDK CORPORATION (JP) 2009-10-29 US disclosed
US-20090226658-A1 Optical Recording Medium TDK CORPORATION (JP) 2009-09-10 US disclosed
US-20090226658-A1 Optical Recording Medium TDK CORPORATION (JP) 2009-09-10 US disclosed
US-20090149660-A1 OPTICAL RECORDING MATERIAL AND OPTICAL RECORDING MEDIA TDK CORPORATION (JP) 2009-06-11 US disclosed
US-20090149660-A1 OPTICAL RECORDING MATERIAL AND OPTICAL RECORDING MEDIA TDK CORPORATION (JP) 2009-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149660-A1 OPTICAL RECORDING MATERIAL AND OPTICAL RECORDING MEDIA KCNN4, CACNA1E, KCNN2 MAPT 1924/4885ALDH1A1 1253/4885RAB9A 1038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.