Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7228426 | 0.88 | GAA (0.44) | NPSR1OPRL1ALDH1A1HSD17B10GAA | |
| SCHEMBL7221945 | 0.85 | SMN1; SMN2 (0.41) | NPSR1OPRL1ALDH1A1HSD17B10GAA | |
| SCHEMBL7230273 | 0.83 | OPRL1 (0.44) | NPSR1OPRL1ALDH1A1GAACHRM2 | |
| SCHEMBL7222128 | 0.82 | ALDH1A1 (0.53) | NPSR1OPRL1ALDH1A1HSD17B10CHRM2 | |
| SCHEMBL7222159 | 0.78 | SMN1; SMN2 (0.52) | NPSR1OPRL1ALDH1A1HSD17B10GAA | |
| SCHEMBL22629830 | 0.76 | HSD11B1 (0.40) | NPSR1OPRL1ALDH1A1CHRM2CHRM4 | |
| SCHEMBL7224279 | 0.74 | ALDH1A1 (0.46) | NPSR1OPRL1ALDH1A1GAACHRM2 | |
| SCHEMBL22629246 | 0.73 | HSD11B1 (0.40) | NPSR1OPRL1ALDH1A1GAACHRM2 | |
| SCHEMBL7688352 | 0.73 | HSD11B1 (0.39) | NPSR1OPRL1CHRM2CHRM4CHRM5 | |
| SCHEMBL7224072 | 0.72 | CHRNB2 (0.43) | NPSR1OPRL1ALDH1A1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6573275-B1 | Insecticidal compositions comprising and to methods of combatting and controlling insect pests therewith. | SYNGENTA LIMITED (GB) | 2003-06-03 | — | — | US | disclosed |
| EP-0828739-B1 | BICYCLIC AMINES AS INSECTICIDES | SYNGENTA LTD (GB) | 2002-09-11 | — | — | EP | disclosed |
| US-6391883-B1 | INSECTICIDES | SYNGENTA LIMITED (GB) | 2002-05-21 | — | — | US | disclosed |
| US-6207676-B1 | Bicyclic amines | ZENECA LIMITED (GB) | 2001-03-27 | — | — | US | disclosed |
| EP-0828739-A1 | BICYCLIC AMINES AS INSECTICIDES | ZENECA LIMITED (GB) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037494-A1 | BICYCLIC AMINES AS INSECTICIDES | ZENECA LIMITED (GB) | 1996-11-28 | — | — | WO | disclosed |