Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 5/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.34 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273086 | 0.81 | TET2 (0.46) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL517189 | 0.79 | TET2 (0.39) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL15484379 | 0.79 | TET2 (0.37) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL474841 | 0.79 | ALDH1A1 (0.56) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL3312697 | 0.73 | TSHR (0.62) | TET2ALOX15HSD17B10LMNAALDH1A1 | |
| SCHEMBL26631 | 0.73 | LMNA (0.56) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL304951 | 0.73 | TET2 (0.40) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL4867078 | 0.73 | — | — | |
| SCHEMBL10663570 | 0.73 | LMNA (0.56) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL9293056 | 0.72 | HDAC3 (0.46) | TET2TET3TET1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8727135-B2 | Composite filtration membranes and methods of preparation thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-05-20 | — | — | US | disclosed |
| US-20120048798-A1 | COMPOSITE FILTRATION MEMBRANES AND METHODS OF PREPARATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-03-01 | — | — | US | disclosed |