Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | CRHBP | P24387 | 1/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6044176 | 0.89 | HCAR3 (1.00) | HCAR3MAPTNPC1PKMALDH1A1 | |
| SCHEMBL6044024 | 0.85 | HCAR3 (1.00) | HCAR3MAPTNPC1PKMALDH1A1 | |
| SCHEMBL11238552 | 0.85 | HCAR3 (0.77) | HCAR3MAPTNPC1PKMALDH1A1 | |
| SCHEMBL11208444 | 0.84 | HCAR3 (0.97) | HCAR3MAPTNPC1PKMALDH1A1 | |
| SCHEMBL6044600 | 0.84 | HCAR3 (0.97) | HCAR3MAPTNPC1PKMALDH1A1 | |
| SCHEMBL11242963 | 0.84 | HCAR3 (0.97) | HCAR3MAPTNPC1PKMALDH1A1 | |
| SCHEMBL9192588 | 0.83 | HCAR3 (0.77) | HCAR3MAPTNPC1PKMALDH1A1 | |
| SCHEMBL7230677 | 0.83 | HCAR3 (0.59) | HCAR3MAPTNPC1PKMALDH1A1 | |
| SCHEMBL8509227 | 0.82 | HCAR3 (0.69) | HCAR3MAPTNPC1PKMALDH1A1 | |
| SCHEMBL11543635 | 0.82 | HCAR3 (0.57) | HCAR3MAPTNPC1PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344957-A | Benz-acyl-benzimidazole derivatives and antiallergic compositions | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4213993-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| US-4141982-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |