Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12743946 | 0.82 | RAB9A (0.61) | MAPTKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL723432 | 0.80 | SMN1; SMN2 (0.48) | MAPTKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL28581898 | 0.79 | RAB9A (0.43) | MAPTKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL6506544 | 0.79 | L3MBTL1 (0.46) | MAPTKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL8699745 | 0.79 | CYP1A2 (0.56) | MAPTKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL28889596 | 0.78 | RAB9A (0.42) | MAPTKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL10035777 | 0.77 | RAB9A (0.56) | MAPTKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL559558 | 0.77 | SMN1; SMN2 (0.59) | MAPTKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1149391 | 0.71 | CYP2A6 (0.58) | MAPTPOLBSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3814446 | 0.71 | ALDH1A1 (0.50) | MAPTKMT2AMEN1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616453-A2 | ANTIMETASTATIC COMPOUNDS | Brigham Young University (US) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012027392-A2 | ANTIMETASTATIC COMPOUNDS | BRIGHAM YOUNG UNIVERSITY (US) | 2012-03-01 | — | — | WO | disclosed |