Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.48 |
| ▸ | TACR2 | P21452 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14856188 | 0.96 | ALDH1A1 (0.64) | ALDH1A1KDM4ERAB9ACHEK1NPC1 | |
| SCHEMBL14856189 | 0.96 | ALDH1A1 (0.64) | ALDH1A1KDM4ERAB9ACHEK1NPC1 | |
| SCHEMBL13162947 | 0.81 | ALDH1A1 (0.74) | ALDH1A1KDM4ERAB9ACHEK1NPC1 | |
| SCHEMBL26008657 | 0.81 | ALDH1A1 (1.00) | ALDH1A1KDM4ERAB9ACHEK1NPC1 | |
| SCHEMBL14857155 | 0.80 | ALDH1A1 (0.68) | ALDH1A1KDM4ERAB9ACHEK1NPC1 | |
| SCHEMBL14857154 | 0.80 | ALDH1A1 (0.68) | ALDH1A1KDM4ERAB9ACHEK1NPC1 | |
| SCHEMBL5740904 | 0.79 | CRBN (0.71) | CRBN | |
| SCHEMBL15087624 | 0.78 | RAB9A (0.75) | ALDH1A1KDM4ERAB9ACHEK1NPC1 | |
| SCHEMBL8381645 | 0.78 | RAB9A (0.75) | ALDH1A1KDM4ERAB9ACHEK1NPC1 | |
| SCHEMBL14856587 | 0.76 | RAB9A (0.61) | ALDH1A1KDM4ERAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053171-A1 | Nitrogen-Containing Fused Heterocyclic Compounds and Their use as Beta Amyloid Production Inhibitors | EISAI R&D MANAGEMENT CO., LTD., (JP) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053171-A1 | Nitrogen-Containing Fused Heterocyclic Compounds and Their use as Beta Amyloid Production Inhibitors | BACE1, APP, PSEN1 | ALDH1A1 3158/4885KDM4E 3198/4885RAB9A 1997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.