Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7235507 | 0.85 | MAPT (0.42) | LMNATP53SMN1; SMN2KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL7240261 | 0.83 | GRM1 (0.47) | LMNATP53SMN1; SMN2HPGDGAA | |
| Hydrochloric Acid SCHEMBL7232019 | 0.83 | GRM1 (0.39) | LMNATP53SMN1; SMN2HPGDNPC1 | |
| Hydrochloric Acid SCHEMBL7233122 | 0.82 | GRM1 (0.46) | LMNATP53SMN1; SMN2HPGDNPC1 | |
| SCHEMBL7232091 | 0.82 | ATM (0.47) | LMNATP53SMN1; SMN2KMT2AGAA | |
| SCHEMBL7239242 | 0.81 | SMN1; SMN2 (0.42) | LMNATP53SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL7231898 | 0.80 | LMNA (0.39) | LMNATP53SMN1; SMN2KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL7242414 | 0.79 | SMN1; SMN2 (0.42) | LMNATP53SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL7238022 | 0.79 | NPC1 (0.42) | LMNATP53SMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7234112 | 0.78 | NPC1 (0.42) | LMNATP53SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642264-B1 | Thiazolo(3,2-a)benzoimidazole derivatives act specifically on metabotropic glutamate receptors and are used as medicaments. | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2003-11-04 | — | — | US | disclosed |
| EP-1167369-A1 | NOVEL THIAZOLOBENZIMIDAZOLE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |