Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | GBA1 | P04062 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7227791 | 0.89 | MAOA (0.74) | KDM4EKCNJ1SMN1; SMN2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8661674 | 0.87 | MAOA (0.72) | KDM4EKCNJ1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2206628 | 0.81 | KDM4E (0.73) | KDM4EKCNJ1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3156886 | 0.81 | KDM4E (0.73) | KDM4EKCNJ1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1805498 | 0.80 | KDM4E (0.71) | KDM4EKCNJ1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8329627 | 0.80 | KDM4E (0.71) | KDM4EKCNJ1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3143167 | 0.80 | KDM4E (0.71) | KDM4EKCNJ1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL23832519 | 0.79 | KDM4E (0.69) | KDM4EKCNJ1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5626457 | 0.79 | ALDH1A1 (0.74) | KDM4EKCNJ1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL15340821 | 0.79 | KDM4E (0.59) | KDM4EKCNJ1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6545035-B1 | Having effect on various kinases and cycline/CDK complexes and on the proliferation of various tumour cells. | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-04-08 | — | — | US | disclosed |
| US-6319918-B1 | FOR LYMPHOMA OR SOLID TUMORS TREATMENT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-11-20 | — | — | US | disclosed |